Cardiac amyloidosis is a rare disease in which amyloid depositions in the heart muscle lead to wall thickening. In echocardiography, the walls appear massively thickened, with wall thicknesses of more than 20mm. Since the increased wall thickness results from amyloid depositions rather than muscle hypertrophy, the ECG shows no signs of hypertrophy. Instead, very low QRS complexes are found. This is therefore called paradoxical LVH.
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